Publications

2023

 

Mutagenic Incorporation of Inosine into DNA via T:I mismatch Formation by Human DNA Polymerase Eta (polη).   Biochemical Journal  480 (9), 649-664, 2023  (https://doi.org/10.1042/BCJ20230029)

Jameson R. Averill and Hunmin Jung*         * Corresponding Author

 

2022

 

Contributing Factors for Mutagenic DNA Lesion Bypass by DNA Polymerase Eta (polη).   DNA.  2(4), 205-220, 2022 (https://doi.org/10.3390/dna2040015)

    Hunmin Jung*         * Corresponding Author

     

    Effects of N7-akylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η.   Chemical Research in Toxicology.  35(3), 512-521, 2022  (https://doi.org/10.1021/acs.chemrestox.1c00416)

      Hunmin Jung, Naveen Kumar Rayala, and Seongmin Lee

       

      2021

      Insights into the Mismatch Discrimination Mechanism of Y-family DNA Polymerase Dpo4.  Biochemical Journal 478 (9), 1769-1781, 2021 (https://doi.org/10.1042/BCJ20210162)

      Hunmin Jung and Seongmin Lee

       

      2020

      Structural Insights into the Bypass of the Major Deaminated Purines by Translesion Synthesis DNA Polymerase.  Biochemical Journal 477 (24), 4797-4810, 2020 (Selected for the Featured Cover of the issue, and Commentary on Biochemical Journal 478 (7), 1309-1313, 2021) (https://doi.org/10.1042/BCJ20200800)

      Hunmin Jung, Michael Hawkins, and Seongmin Lee

       

      Translesion Synthesis of the Major Nitrogen Mustard-Induced DNA Lesion by Human DNA Polymerase η.  Biochemical Journal 477 (23), 4543-4558, 2020  (https://doi.org/10.1042/BCJ20200767)

      Hunmin Jung, Rayala Naveen Kumar, and Seongmin Lee

       

      The Structure of Importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-Importin α interactions.  Biochemical Journal 477 (17), 3253-3269, 2020 (https://doi.org/10.1042/BCJ20200520)

      Hunmin Jung, Tomomi Takeshima, Tsutomu Nakagawa, Karen MacMillan, Richard Max Wynn, Hanzhi Wang, Haruhiko Sakiyama, Shuguang Wei, Yang Li, Richard K Bruick, Bruce A Posner, Jef K De Brabander, and Kosaku Uyeda

       

      Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.  Biochemical Journal 477 (15), 2859-2871, 2020  (https://doi.org/10.1042/BCJ20200449)

      Hunmin Jung and Seongmin Lee

       

      Mutagenesis Mechanism of the Major Oxidative Adenine Lesion 7,8-dihydro-8-oxoadenine.  Nucleic Acids Research 48 (9), 5119-5134, 2020  (https://doi.org/10.1093/nar/gkaa193)

      Myong-Chul Koag*, Hunmin Jung*, and Seongmin Lee (* Co-first authors)

       

      Catalytic Mechanism of the Mismatch-Specific DNA Glycosylase Methyl-CpG-Binding Domain 4. Biochemical Journal 477 (9), 1601-1612, 2020  (https://doi.org/10.1042/BCJ20200125)

      Hala Ouzon-Shubeita*, Hunmin Jung*, Michelle Lee, Myong-Chul Koag, and Seongmin Lee (* Co-first authors)

       

      2019

      Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. Journal of the American Chemical Society 141 (11), 4584-4596, 2019  (https://doi.org/10.1021/jacs.8b08551)

      Myong-Chul Koag, Hunmin Jung, and Seongmin Lee

       

      Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η. Molecules 24 (21), 3928, 2019  (https://doi.org/10.3390/molecules24213928)

      Myong-Chul Koag, Hunmin Jung, Yi Kou, and Seongmin Lee

       

      2017

      Copper Metallothioneins. IUBMB Life 69 (4), 236-245, 2017

      Jenifer Calvo*, Hunmin Jung*, and Gabriele Meloni (* Co-first authors)

       

      2016

      Metabolite Regulation of Nuclear Localization of Carbohydrate Response Element-binding Protein (ChREBP). Role of AMP as an Allosteric Inhibitor. Journal of Biological Chemistry 291 (20), 10515-10527, 2016

      Shogo Sato, Hunmin Jung, Tsutomu Nakagawa, Robert Pawlosky, Tomomi Takeshima, Wan-Ru Lee, Haruhiko Sakiyama, Sunil Laxman, R. Max Wynn, Benjamin Tu, John B. MacMillan, Jef K. De Brabander, Richard L. Veech, and Kosaku Uyeda

       

      2015

      The Identification of Novel Mycobacterium tuberculosis DHFR Inhibitors and the Investigation of Their Binding Preferences by Using Molecular Modelling. Scientific Reports 5, 14328, 2015

      Wei Hong, Yu Wang, Zhe Chang, Yanhui Yang, Jing Pu, Tao Sun, Sargit Kaur, James C. Sacchettini, Hunmin Jung, Wee Lin Wong, Lee Fah Yap, Yun Fong Ngeow, Ian C. Paterson, and Hao Wang

       

      2014

      Folate Pathway Disruption Leads to Critical Disruption of Methionine Derivatives in Mycobacterium tuberculosis. Chemistry & Biology 21 (7), 819-830, 2014

      Molly R. Nixon, Kurt W. Saionz, Mi-Sun Koo, Michael J. Szymonifka, Hunmin Jung, Justin P. Roberts, Madhumita Nandakumar, Anuradha Kumar, Reiling Liao, Tige Rustad, James C. Sacchettini, Kyu Y. Rhee, Joel S. Freundlich, and David R. Sherman