2024
Connecting Dots between Nucleotide Biosynthesis and DNA Lesion Repair/Bypass in Cancer. Bioscience Reports Accepted
Jackson C. Lin, Ayobami Oludare, and Hunmin Jung* * Corresponding Author
Novel insights into the role of translesion synthesis polymerase in DNA incorporation and bypass of 5-fluorouracil in colorectal cancer. Nucleic Acids Research 52 (8), 4295-4312, 2024 (https://doi.org/10.1093/nar/gkae102)
Jameson R. Averill, Jackson C. Lin, John Jung, and Hunmin Jung* * Corresponding Author
2023
Mutagenic Incorporation of Inosine into DNA via T:I mismatch Formation by Human DNA Polymerase Eta (polη). Biochemical Journal 480 (9), 649-664, 2023 (https://doi.org/10.1042/BCJ20230029)
Jameson R. Averill and Hunmin Jung* * Corresponding Author
2022
Contributing Factors for Mutagenic DNA Lesion Bypass by DNA Polymerase Eta (polη). DNA. 2(4), 205-220, 2022 (https://doi.org/10.3390/dna2040015)
Hunmin Jung* * Corresponding Author
Effects of N7-akylguanine Conformation and Metal Cofactors on the Translesion Synthesis by Human DNA Polymerase η. Chemical Research in Toxicology. 35(3), 512-521, 2022 (https://doi.org/10.1021/acs.chemrestox.1c00416)
Hunmin Jung, Naveen Kumar Rayala, and Seongmin Lee
2021
Insights into the Mismatch Discrimination Mechanism of Y-family DNA Polymerase Dpo4. Biochemical Journal 478 (9), 1769-1781, 2021 (https://doi.org/10.1042/BCJ20210162)
Hunmin Jung and Seongmin Lee
2020
Structural Insights into the Bypass of the Major Deaminated Purines by Translesion Synthesis DNA Polymerase. Biochemical Journal 477 (24), 4797-4810, 2020 (Selected for the Featured Cover of the issue, and Commentary on Biochemical Journal 478 (7), 1309-1313, 2021) (https://doi.org/10.1042/BCJ20200800)
Hunmin Jung, Michael Hawkins, and Seongmin Lee
Translesion Synthesis of the Major Nitrogen Mustard-Induced DNA Lesion by Human DNA Polymerase η. Biochemical Journal 477 (23), 4543-4558, 2020 (https://doi.org/10.1042/BCJ20200767)
Hunmin Jung, Rayala Naveen Kumar, and Seongmin Lee
The Structure of Importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-Importin α interactions. Biochemical Journal 477 (17), 3253-3269, 2020 (https://doi.org/10.1042/BCJ20200520)
Hunmin Jung, Tomomi Takeshima, Tsutomu Nakagawa, Karen MacMillan, Richard Max Wynn, Hanzhi Wang, Haruhiko Sakiyama, Shuguang Wei, Yang Li, Richard K Bruick, Bruce A Posner, Jef K De Brabander, and Kosaku Uyeda
Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4. Biochemical Journal 477 (15), 2859-2871, 2020 (https://doi.org/10.1042/BCJ20200449)
Hunmin Jung and Seongmin Lee
Mutagenesis Mechanism of the Major Oxidative Adenine Lesion 7,8-dihydro-8-oxoadenine. Nucleic Acids Research 48 (9), 5119-5134, 2020 (https://doi.org/10.1093/nar/gkaa193)
Myong-Chul Koag*, Hunmin Jung*, and Seongmin Lee (* Co-first authors)
Catalytic Mechanism of the Mismatch-Specific DNA Glycosylase Methyl-CpG-Binding Domain 4. Biochemical Journal 477 (9), 1601-1612, 2020 (https://doi.org/10.1042/BCJ20200125)
Hala Ouzon-Shubeita*, Hunmin Jung*, Michelle Lee, Myong-Chul Koag, and Seongmin Lee (* Co-first authors)
2019
Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. Journal of the American Chemical Society 141 (11), 4584-4596, 2019 (https://doi.org/10.1021/jacs.8b08551)
Myong-Chul Koag, Hunmin Jung, and Seongmin Lee
Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η. Molecules 24 (21), 3928, 2019 (https://doi.org/10.3390/molecules24213928)
Myong-Chul Koag, Hunmin Jung, Yi Kou, and Seongmin Lee
2017
Copper Metallothioneins. IUBMB Life 69 (4), 236-245, 2017
Jenifer Calvo*, Hunmin Jung*, and Gabriele Meloni (* Co-first authors)
2016
Metabolite Regulation of Nuclear Localization of Carbohydrate Response Element-binding Protein (ChREBP). Role of AMP as an Allosteric Inhibitor. Journal of Biological Chemistry 291 (20), 10515-10527, 2016
Shogo Sato, Hunmin Jung, Tsutomu Nakagawa, Robert Pawlosky, Tomomi Takeshima, Wan-Ru Lee, Haruhiko Sakiyama, Sunil Laxman, R. Max Wynn, Benjamin Tu, John B. MacMillan, Jef K. De Brabander, Richard L. Veech, and Kosaku Uyeda
2015
The Identification of Novel Mycobacterium tuberculosis DHFR Inhibitors and the Investigation of Their Binding Preferences by Using Molecular Modelling. Scientific Reports 5, 14328, 2015
Wei Hong, Yu Wang, Zhe Chang, Yanhui Yang, Jing Pu, Tao Sun, Sargit Kaur, James C. Sacchettini, Hunmin Jung, Wee Lin Wong, Lee Fah Yap, Yun Fong Ngeow, Ian C. Paterson, and Hao Wang
2014
Folate Pathway Disruption Leads to Critical Disruption of Methionine Derivatives in Mycobacterium tuberculosis. Chemistry & Biology 21 (7), 819-830, 2014
Molly R. Nixon, Kurt W. Saionz, Mi-Sun Koo, Michael J. Szymonifka, Hunmin Jung, Justin P. Roberts, Madhumita Nandakumar, Anuradha Kumar, Reiling Liao, Tige Rustad, James C. Sacchettini, Kyu Y. Rhee, Joel S. Freundlich, and David R. Sherman